LIPOXYGENASE 1
\lˈɪpəksˌɪd͡ʒənˌe͡ɪs wˈɒn], \lˈɪpəksˌɪdʒənˌeɪs wˈɒn], \l_ˈɪ_p_ə_k_s_ˌɪ_dʒ_ə_n_ˌeɪ_s w_ˈɒ_n]\
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An enzyme of the oxidoreductase class that catalyzes reactions between linoleate and other fatty acids and oxygen to form hydroperoxy-fatty acid derivatives. Related enzymes in this class include the ARACHIDONATE LIPOXYGENASES; ARACHIDONATE 5-LIPOXYGENASE; ARACHIDONATE 12-LIPOXYGENASE; and ARACHIDONATE 15-LIPOXYGENASE. EC 1.13.11.12.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.