LEWIS LUNG CARCINOMA
\lˈuːiz lˈʌŋ kˌɑːsɪnˈə͡ʊmə], \lˈuːiz lˈʌŋ kˌɑːsɪnˈəʊmə], \l_ˈuː_i_z l_ˈʌ_ŋ k_ˌɑː_s_ɪ_n_ˈəʊ_m_ə]\
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A carcinoma discovered by Dr. Margaret R. Lewis of the Wistar Institute in 1951. This tumor originated spontaneously as a carcinoma of the lung of a C57BL mouse. The tumor does not appear to be grossly hemorrhagic and the majority of the tumor tissue is a semifirm homogeneous mass. (From Cancer Chemother Rep 2 1972 Nov; (3)1:325) It is also called 3LL and LLC and is used as a transplantable malignancy.
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.