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(1 beta,2 alpha,11 beta,12 alpha,15 beta (S))-11,20-Epoxy-1,2,11,12-tetrahydroxy-15- (2-hydroxy-2-methyl-1-oxobutoxy)picras-3-en-16-one. A quassinoid (Simaroubolide) from Simaruba glauca, a tropical shrub. It has been used as an antiamebic agent and is found to be cytotoxic. It may be of use in cancer chemotherapy.