INTERFERON ALPHA
\ˌɪntəfˈi͡əɹən ˈalfə], \ˌɪntəfˈiəɹən ˈalfə], \ˌɪ_n_t_ə_f_ˈiə_ɹ_ə_n ˈa_l_f_ə]\
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One of the type I interferons (INTERFERON TYPE I) produced by peripheral blood leukocytes or lymphoblastoid cells when exposed to live or inactivated virus, double-stranded RNA, or bacterial products. It is the major interferon produced by virus-induced leukocyte cultures and, in addition to its pronounced antiviral activity, it causes activation of NK cells.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.