INTEGRIN ALPHA(M)BETA(2)
\ɪntˈɛɡɹɪn ˈalfə ˈɛm bˈiːtə tˈuː], \ɪntˈɛɡɹɪn ˈalfə ˈɛm bˈiːtə tˈuː], \ɪ_n_t_ˈɛ_ɡ_ɹ_ɪ_n ˈa_l_f_ə__ ˈɛ_m__ b_ˈiː_t_ə__ t_ˈuː]\
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An adhesion-promoting leukocyte surface membrane heterodimer. The alpha subunit consists of the CD11b antigen and the beta subunit of the CD18 antigen (ANTIGENS, CD18). The antigen, which is an integrin, functions both as a receptor for complement 3 and in cell-cell and cell-substrate adhesive interactions.
By DataStellar Co., Ltd