INORGANIC ARSENIC POISONINGS
\ˌɪnɔːɡˈanɪk ˈɑːsnɪk pˈɔ͡ɪzənɪŋz], \ˌɪnɔːɡˈanɪk ˈɑːsnɪk pˈɔɪzənɪŋz], \ˌɪ_n_ɔː_ɡ_ˈa_n_ɪ_k ˈɑː_s_n_ɪ_k p_ˈɔɪ_z_ə_n_ɪ_ŋ_z]\
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Disorders associated with acute or chronic exposure to compounds containing ARSENIC (ARSENICALS) which may be fatal. Acute oral ingestion is associated with gastrointestinal symptoms and an encephalopathy which may manifest as SEIZURES, mental status changes, and COMA. Chronic exposure is associated with mucosal irritation, desquamating rash, myalgias, peripheral neuropathy, and white transverse (Mees) lines in the fingernails. (Adams et al., Principles of Neurology, 6th ed, p1212)
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Word of the day
Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.