INK4A PROTEIN
\ˌa͡ɪˌɛnkˈe͡ɪ fˈɔːɹ ˈe͡ɪ pɹˈə͡ʊtiːn], \ˌaɪˌɛnkˈeɪ fˈɔːɹ ˈeɪ pɹˈəʊtiːn], \ˌaɪ_ˌɛ_n_k_ˈeɪ f_ˈɔː_ɹ ˈeɪ p_ɹ_ˈəʊ_t_iː_n]\
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A gene product of the p16 tumor suppressor gene (GENES, P16). It is also called INK4 or INK4A because it is the prototype member the INK4 family - inhibitors of cyclin-dependent kinase CDK4. This protein is produced from the alpha mRNA transcript of the p16 gene. The other gene product, produced from the alternatively spliced beta transcript, is P14ARF PROTEIN. Both p16 gene products have tumor suppressor functions.
By DataStellar Co., Ltd
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Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.