INFANTILE BOTULISM
\ˈɪnfəntˌa͡ɪl bˈɒtjuːlˌɪzəm], \ˈɪnfəntˌaɪl bˈɒtjuːlˌɪzəm], \ˈɪ_n_f_ə_n_t_ˌaɪ_l b_ˈɒ_t_j_uː_l_ˌɪ_z_ə_m]\
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A disease caused by potent protein NEUROTOXINS produced by CLOSTRIDIUM BOTULINUM which interfere with the presynaptic release of ACETYLCHOLINE at the NEUROMUSCULAR JUNCTION. Clinical features include abdominal pain, vomiting, acute PARALYSIS (including respiratory paralysis), blurred vision, and DIPLOPIA. Botulism may be classified into several subtypes (e.g., food-borne, infant, wound, and others). (From Adams et al., Principles of Neurology, 6th ed, p1208)
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Word of the day
tinctura quininae ammoniata
- A preparation made by dissolving quinin sulphate in alcohol [Br. Ph.].