IMMUNOSUPPRESSIVE AGENTS
\ɪmjˈuːnəsəpɹˌɛsɪv ˈe͡ɪd͡ʒənts], \ɪmjˈuːnəsəpɹˌɛsɪv ˈeɪdʒənts], \ɪ_m_j_ˈuː_n_ə_s_ə_p_ɹ_ˌɛ_s_ɪ_v ˈeɪ_dʒ_ə_n_t_s]\
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Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of suppressor T-cell populations or by inhibiting the activation of helper cells. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of interleukins and other cytokines are emerging.
By DataStellar Co., Ltd
Word of the day
Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.