HUMAN ARTIFICIAL CHROMOSOME
\hjˈuːmən ˌɑːtɪfˈɪʃə͡l kɹˈə͡ʊməsˌə͡ʊm], \hjˈuːmən ˌɑːtɪfˈɪʃəl kɹˈəʊməsˌəʊm], \h_j_ˈuː_m_ə_n ˌɑː_t_ɪ_f_ˈɪ_ʃ_əl k_ɹ_ˈəʊ_m_ə_s_ˌəʊ_m]\
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DNA constructs that are composed of, at least, all elements, such as a REPLICATION ORIGIN; TELOMERE; and CENTROMERE, required for successful replication, propagation to and maintainance in progeny human cells. In addition, they are constructed to carry other sequences for analysis or gene transfer.
By DataStellar Co., Ltd