HTLV III GP41
\ˌe͡ɪt͡ʃtˌiːˌɛlvˈiː ɹˌə͡ʊmən θɹˈiː d͡ʒˌiːpˈiː fˈɔːtiwˈɒn], \ˌeɪtʃtˌiːˌɛlvˈiː ɹˌəʊmən θɹˈiː dʒˌiːpˈiː fˈɔːtiwˈɒn], \ˌeɪ_tʃ_t_ˌiː__ˌɛ_l_v_ˈiː ɹ_ˌəʊ_m_ə_n_ θ_ɹ_ˈiː dʒ_ˌiː_p_ˈiː f_ˈɔː_t_i_w_ˈɒ_n]\
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Transmembrane envelope protein of the human immunodeficiency virus which is encoded by the HIV env gene. It has a molecular weight of 41,000 and is glycosylated. The N-terminal part of gp41 is thought to be involved in cell fusion with the CD4 antigens of T4 lymphocytes, leading to syncytial formation. Gp41 is one of the most common HIV antigens detected by immunoblotting.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.