HIV VPU GENE PRODUCT
\ˌe͡ɪt͡ʃˌa͡ɪvˈiː vˌiːpˌiːjˈuː d͡ʒˈiːn pɹˈɒdʌkt], \ˌeɪtʃˌaɪvˈiː vˌiːpˌiːjˈuː dʒˈiːn pɹˈɒdʌkt], \ˌeɪ_tʃ_ˌaɪ_v_ˈiː v_ˌiː_p_ˌiː_j_ˈuː dʒ_ˈiː_n p_ɹ_ˈɒ_d_ʌ_k_t]\
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Non-glycosylated, membrane-associated, 16 kDa proteins which are expressed in large amounts in cells infected with HIV-1. The proteins are required for efficient virion maturation and release. They are not present in HIV-2 nor in SIV. vpu is short for viral protein U, with U undefined.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.