HIV TRS ART GENE PROTEIN
\ˌe͡ɪt͡ʃˌa͡ɪvˈiː tˌiːˌɑːɹˈɛs ˈɑːt d͡ʒˈiːn pɹˈə͡ʊtiːn], \ˌeɪtʃˌaɪvˈiː tˌiːˌɑːɹˈɛs ˈɑːt dʒˈiːn pɹˈəʊtiːn], \ˌeɪ_tʃ_ˌaɪ_v_ˈiː t_ˌiː__ˌɑː_ɹ_ˈɛ_s ˈɑː_t dʒ_ˈiː_n p_ɹ_ˈəʊ_t_iː_n]\
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Trans-acting nuclear proteins whose functional expression are required for HIV viral replication. Specifically, the rev gene products are required for processing and translation of the HIV gag and env mRNAs, and thus rev regulates the expression of the viral structural proteins. rev can also regulate viral regulatory proteins. A cis-acting antirepression sequence (CAR) in env, also known as the rev-responsive element (RRE), is responsive to the rev gene product. rev is short for regulator of virion.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.