GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR
\ɡɹanjˈʊləsˌa͡ɪt mˈakɹəfɪd͡ʒ kˈɒlənɪ stˈɪmjʊlˌe͡ɪtɪŋ fˈaktə], \ɡɹanjˈʊləsˌaɪt mˈakɹəfɪdʒ kˈɒlənɪ stˈɪmjʊlˌeɪtɪŋ fˈaktə], \ɡ_ɹ_a_n_j_ˈʊ_l_ə_s_ˌaɪ_t m_ˈa_k_ɹ_ə_f_ɪ_dʒ k_ˈɒ_l_ə_n_ɪ s_t_ˈɪ_m_j_ʊ_l_ˌeɪ_t_ɪ_ŋ f_ˈa_k_t_ə]\
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An acidic glycoprotein of MW 23 kDa with internal disulfide bonds. The protein is produced in response to a number of inflammatory mediators by mesenchymal cells present in the hemopoietic environment and at peripheral sites of inflammation. GM-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from fetal liver progenitor cells. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages.
By DataStellar Co., Ltd
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.
Nearby Words
- granuloblast
- granulocyte
- granulocyte chemotactic peptide interleukin 8
- granulocyte colony stimulating factor
- granulocyte elastase
- Granulocyte Macrophage Colony Stimulating Factor
- granulocyte macrophage colony stimulating factors, recombinant
- granulocytes
- granulocytic
- granulocytic leukemia
- granulocytic leukemias