GOBLET CELL CARCINOID
\ɡˈɒblət sˈɛl kˈɑːsɪnˌɔ͡ɪd], \ɡˈɒblət sˈɛl kˈɑːsɪnˌɔɪd], \ɡ_ˈɒ_b_l_ə_t s_ˈɛ_l k_ˈɑː_s_ɪ_n_ˌɔɪ_d]\
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A usually small, slow-growing neoplasm composed of islands of rounded, oxyphilic, or spindle-shaped cells of medium size, with moderately small vesicular nuclei, and covered by intact mucosa with a yellow cut surface. The tumor can occur anywhere in the gastrointestinal tract (and in the lungs and other sites); approximately 90% arise in the appendix. It is now established that these tumors are of neuroendocrine origin and derive from a primitive stem cell. (From Stedman, 25th ed & Holland et al., Cancer Medicine, 3d ed, p1182)
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Word of the day
Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.
Nearby Words
- gobio gobio
- gobioid
- gobl
- goblet
- goblet cell
- Goblet Cell Carcinoid
- goblet cell carcinoids
- goblet cells
- goblet, emetic
- goblet-cell
- goblet-cells