GASTRIC ANTRAL VASCULAR ECTASIA
\ɡˈastɹɪk ˈantɹə͡l vˈaskjʊləɹ ɛktˈe͡ɪzi͡ə], \ɡˈastɹɪk ˈantɹəl vˈaskjʊləɹ ɛktˈeɪziə], \ɡ_ˈa_s_t_ɹ_ɪ_k ˈa_n_t_ɹ_əl v_ˈa_s_k_j_ʊ_l_ə_ɹ ɛ_k_t_ˈeɪ_z_iə]\
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A capillary ectasia of the gastric antrum mucosa characterized by thickened, red vascular folds radiating longitudinally from the pylorus to the antrum and resembling, upon endoscopic examination, the stripes on the skin of a ripened watermelon. Histological characteristics include dilated mucosal capillaries, focal thrombosis, and fibromuscular hypertrophy of the lamina propria. It is a cause of chronic upper gastrointestinal bleeding.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.