FRP 1 PROTEIN
\ˌɛfˌɑːpˈiː wˈɒn pɹˈə͡ʊtiːn], \ˌɛfˌɑːpˈiː wˈɒn pɹˈəʊtiːn], \ˌɛ_f_ˌɑː_p_ˈiː w_ˈɒ_n p_ɹ_ˈəʊ_t_iː_n]\
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A heterodimeric protein that is a cell surface antigen associated with lymphocyte activation. The initial characterization of this protein revealed one identifiable heavy chain (CD98 HEAVY CHAIN) and an indeterminate smaller light chain. It is now known that a variety of light chain subunits (CD98 LIGHT CHAINS) can dimerize with the heavy chain. Depending upon its light chain composition a diverse array of functions can be found for this protein. Functions include: type L amino acid transport, type y+L amino acid transport and regulation of cellular fusion.
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Idiopathic Hypercatabolic Hypoproteinemias
- series of gastrointestinal disorders which share in common excessive loss protein, mainly albumin, across gut wall. occur stomach (Menetrier disease), as well the small bowel (intestinal lymphangiectases, assorted inflammatory states). They are also occasionally associated with congestive heart failure (again a bowel protein loss).