FOCAL TONIC SEIZURE
\fˈə͡ʊkə͡l tˈɒnɪk sˈiːʒə], \fˈəʊkəl tˈɒnɪk sˈiːʒə], \f_ˈəʊ_k_əl t_ˈɒ_n_ɪ_k s_ˈiː_ʒ_ə]\
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A disorder characterized by recurrent localized paroxysmal discharges of cerebral neurons that give rise to seizures that have motor manifestations. The majority of partial motor seizures originate in the FRONTAL LOBE (see also EPILEPSY, FRONTAL LOBE). Motor seizures may manifest as tonic or clonic movements involving the face, one limb or one side of the body. A variety of more complex patterns of movement, including abnormal posturing of extremities, may also occur.
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EF 1H
- Peptide elongation factor 1 multisubunit protein that responsible GTP-dependent binding of aminoacyl-tRNAs eukaryotic ribosomes. alpha 1alpha) binds tRNA transfers it ribosome in a process linked to GTP hydrolysis. The beta and delta subunits (1beta, EF-1delta) are involved exchanging GDP for GTP. gamma subunit (1gamma) is structural component.