FLUORESCENT ANTIBODY TECHNIQUE
\flʊ͡əɹˈɛsənt ˈantɪbˌɒdi tɛknˈiːk], \flʊəɹˈɛsənt ˈantɪbˌɒdi tɛknˈiːk], \f_l_ʊə_ɹ_ˈɛ_s_ə_n_t ˈa_n_t_ɪ_b_ˌɒ_d_i t_ɛ_k_n_ˈiː_k]\
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Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.