FILIPIN IV
\fˈɪlɪpˌɪn ɹˌə͡ʊmən fˈɔː], \fˈɪlɪpˌɪn ɹˌəʊmən fˈɔː], \f_ˈɪ_l_ɪ_p_ˌɪ_n ɹ_ˌəʊ_m_ə_n_ f_ˈɔː]\
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A complex of polyene antibiotics obtained from Streptomyces filipinensis. Filipin III alters membrane function by interfering with membrane sterols, inhibits mitochondrial respiration, and is proposed as an antifungal agent. Filipins I, II, and IV are less important.
By DataStellar Co., Ltd
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Acquired Meningomyeloceles
- Congenital, or rarely acquired, herniation meningeal spinal cord tissue through a bony defect vertebral column. majority these defects occur lumbosacral region. features include PARAPLEGIA, loss of sensation in the lower body, and incontinence. This condition may be associated with ARNOLD-CHIARI MALFORMATION HYDROCEPHALUS. (From Joynt, Clinical Neurology, 1992, Ch55, pp35-6)