FIBRINOPEPTIDE A
\fˈɪbɹɪnˌə͡ʊppta͡ɪd ˈe͡ɪ], \fˈɪbɹɪnˌəʊpptaɪd ˈeɪ], \f_ˈɪ_b_ɹ_ɪ_n_ˌəʊ_p_p_t_aɪ_d ˈeɪ]\
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Two small peptide chains removed from the N-terminal segment of the alpha chains of fibrinogen by the action of thrombin during the blood coagulation process. Each peptide chain contains 18 amino acid residues. In vivo, fibrinopeptide A is used as a marker to determine the rate of conversion of fibrinogen to fibrin by thrombin.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.