FEERS DISEASE
\fˈi͡əz dɪzˈiːz], \fˈiəz dɪzˈiːz], \f_ˈiə_z d_ɪ_z_ˈiː_z]\
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A condition seen primarily in childhood, most often resulting from chronic exposure to MERCURY COMPOUNDS which may result in ENCEPHALOPATHY and POLYNEUROPATHY. Clinical features include pain, swelling and pinkish discoloration of the fingers and toes, weakness in the extremities, extreme irritability, HYPERESTHESIA, and alterations in level of consciousness. (From Menkes, Textbook of Child Neurology, 5th ed, p603)
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Word of the day
Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.