FASCICULUS UNCINATUS
\fasˈɪkjʊləs ʌnsˈɪnatəs], \fasˈɪkjʊləs ʌnsˈɪnatəs], \f_a_s_ˈɪ_k_j_ʊ_l_ə_s ʌ_n_s_ˈɪ_n_a_t_ə_s]\
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A white bundle, seen on the lateral aspect of the cerebral hemispheres, passing across the bottom of the fissure of Sylvius, and connecting the anterior with the middle and posterior lobes. The fibres of this fasciculus expand at each extremity, and the superficial portions of them curve or hook sharply between the contiguous parts of the anterior and middle lobes, whence the epithet 'uncinatus.'
By Robley Dunglison
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.