ESTRONE, (9 BETA) ISOMER
\ˈɛstɹə͡ʊn], \ˈɛstɹəʊn], \ˈɛ_s_t_ɹ_əʊ_n]\
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A metabolite of estradiol but possessing less biological activity. It is found in the urine of pregnant women and mares, in the human placenta, and in the urine of bulls and stallions. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), estrone may reasonably be anticipated to be a carcinogen (Merck, 11th ed).
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Collagen Induced Arthritis
- ARTHRITIS that is induced in experimental animals. Immunological and infectious agents can be used to develop models. These methods include injections of stimulators the immune response, such as an adjuvant (ADJUVANTS, IMMUNOLOGIC) or COLLAGEN.