ELEPHANTIASIS OF JAVA
\ˈɛlɪfˌanʃɪˌasiz ɒv d͡ʒˈɑːvə], \ˈɛlɪfˌanʃɪˌasiz ɒv dʒˈɑːvə], \ˈɛ_l_ɪ_f_ˌa_n_ʃ_ɪ__ˌa_s_i_z ɒ_v dʒ_ˈɑː_v_ə]\
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Is likewise a variety of lepra, characterized by large white tumours on the toes and fingers, resembling scrofulous tumefactions. These tumours ulcerate, and the ulcerations spread from the extremities towards the trunk, destroying even the bones. Amputation can alone arrest its progress. The disease is often accompanied by alopecia, and by an eruption of red spots.
By Robley Dunglison
Word of the day
Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.