DISADVANTAGEOUS

\dˌɪsɐdvantˈe͡ɪd͡ʒəs], \dˌɪsɐdvantˈe‍ɪd‍ʒəs], \d_ˌɪ_s_ɐ_d_v_a_n_t_ˈeɪ_dʒ_ə_s]\
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1919 - The Winston Simplified Dictionary
By William Dodge Lewis, Edgar Arthur Singer
 
1899 - The american dictionary of the english language.
By Daniel Lyons
 
1919 - The Concise Standard Dictionary of the English Language
By James Champlin Fernald
 
1790 - A Complete Dictionary of the English Language
By Thomas Sheridan

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Olivopontocerebellar Atrophies

  • group inherited disorders which share progressive ataxia combination with atrophy CEREBELLUM; PONS; inferior olivary nuclei. Additional features include RIGIDITY; NYSTAGMUS; RETINAL DEGENERATION; MUSCLE SPASTICITY; DEMENTIA; URINARY INCONTINENCE; OPHTHALMOPLEGIA. familial has an earlier onset (second decade) and may feature spinal cord atrophy. sporadic form tends to present in the fifth or sixth decade, is considered a clinical subtype MULTIPLE SYSTEM ATROPHY. (From Adams et al., Principles of Neurology, 6th ed, p1085)
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