DIAMINODIPHENYLSULFONE
\dˈa͡ɪəmˌɪnədɪfˌiːna͡ɪlsˌʌlfə͡ʊn], \dˈaɪəmˌɪnədɪfˌiːnaɪlsˌʌlfəʊn], \d_ˈaɪ_ə_m_ˌɪ_n_ə_d_ɪ_f_ˌiː_n_aɪ_l_s_ˌʌ_l_f_əʊ_n]\
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A sulfone active against a wide range of bacteria but mainly employed for its actions against MYCOBACTERIUM LEPRAE. Its mechanism of action is probably similar to that of the SULFONAMIDES which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with PYRIMETHAMINE in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8)
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