DEHYDROBENZPERIDOL
\dˌiːha͡ɪdɹˈə͡ʊbənzpəɹˌɪdɒl], \dˌiːhaɪdɹˈəʊbənzpəɹˌɪdɒl], \d_ˌiː_h_aɪ_d_ɹ_ˈəʊ_b_ə_n_z_p_ə_ɹ_ˌɪ_d_ɒ_l]\
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A butyrophenone with general properties similar to those of HALOPERIDOL. It is used in conjunction with an opioid analgesic such as FENTANYL to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon. It is also used as a premedicant, as an antiemetic, and for the control of agitation in acute psychoses. (From Martindale, The Extra Pharmacopoeia, 29th ed, p593)
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Word of the day
Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.