CYP2E1
\sˈɪp tˈuː ˈiː wˈɒn], \sˈɪp tˈuː ˈiː wˈɒn], \s_ˈɪ_p t_ˈuː ˈiː w_ˈɒ_n]\
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A polymorphic enzyme that activates carcinogenic N-nitrosamines, benzene, urethane, and other low molecular weight compounds. It is inducible by ethanol and metabilizes alcohol. Experimentally, it is used to study the effects of ethanol usage and withdrawal via enzyme markers such as N-nitrosodimethylamine demethylase. (Pharmacogenetics 1995;5 Spec No:S141-4) EC 1.5.99.-.
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