CREUTZFELDT JAKOB SYNDROME
\krjˈuːtsfɛlt d͡ʒˈakɒb sˈɪndɹə͡ʊm], \krjˈuːtsfɛlt dʒˈakɒb sˈɪndɹəʊm], \k_r_j_ˈuː_t_s_f_ɛ_l_t dʒ_ˈa_k_ɒ_b s_ˈɪ_n_d_ɹ_əʊ_m]\
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A rare transmissible encephalopathy most prevalent between the ages of 50 and 70 years. Affected individuals may present with sleep disturbances, personality changes, ATAXIA; APHASIA, visual loss, weakness, muscle atrophy, MYOCLONUS, progressive dementia, and death within one year of disease onset. A familial form exhibiting autosomal dominant inheritance and a new variant CJD (potentially associated with ENCEPHALOPATHY, BOVINE SPONGIFORM) have been described. Pathological features include prominent cerebellar and cerebral cortical spongiform degeneration and the presence of PRIONS. (From N Engl J Med, 1998 Dec 31;339 (27))
By DataStellar Co., Ltd
Word of the day
hydromorphic
- [Greek] Structurally adapted to an aquatic environment, as organs of water plants.
Nearby Words
- cretonne
- cretor
- cretose
- creutzer
- creutzfeldt jakob disease
- Creutzfeldt Jakob Syndrome
- creux
- creux de laisselle
- creuznach, mineral waters of
- creuzot, mineral waters of
- crevalle