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A condition of endemic or inherited idiocy, accompanied by physical degeneracy and deformity (usually with goiter), frequent in certain mountain valleys, esp. of the Alps.

A condition due to congenital lack of thyroid hormone, marked by arrested physical and mental development, dystrophy of the bones and soft parts, and lowered basal metabolism. It is the congenital form of thyroid deficiency, while MYXEDEMA is the acquired form. (From Dorland, 27th ed)

Congenital myxedema, occurring both sporadically and endemically; it appears during the first three years of life and results in an arrest of bodily growth and of mental development, the subjects of the disease being dwarfed idiots.

An Alpine disease, with imperfect development accompanied by dullness of senses.

The condition of a cretin.

The state of a cretin.

A peculiar kind of idiocy, attended with deformity, that prevails in districts about the Alps and other mountains.

(F.) Cretinisme. An epidemic affection in the low, deep, narrow situations of the Valais; in the valley of Aost, Maurienne, a port of Switzerland, the Pyrenees, Tyrol, &c. It is a state of idiocy, commonly accompanied by an enormous goitre, and is often hereditary. The unfortunate cretin is little better than the animals around him. He rarely attains an advanced age. Like idiocy, cretinism has been divided into complete and incomplete.

Endemic idiocy, with deformity, stunted growth, and often with goiter.

A condition of deformity with dwarfed figure, open mouth, and an expressionless idiotic face. The disease is endemic in the Pyrenees, the Alps, and the Himalayas. It is due to loss of function of the thyroid gland.