CONGENITAL TOXOPLASMOSIS
\kənd͡ʒˈɛnɪtə͡l tˌɒksəplɐzmˈə͡ʊsɪs], \kəndʒˈɛnɪtəl tˌɒksəplɐzmˈəʊsɪs], \k_ə_n_dʒ_ˈɛ_n_ɪ_t_əl t_ˌɒ_k_s_ə_p_l_ɐ_z_m_ˈəʊ_s_ɪ_s]\
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Prenatal protozoal infection with TOXOPLASMA gondii which is associated with injury to the developing fetal nervous system. The severity of this condition is related to the stage of pregnancy during which the infection occurs; first trimester infections are associated with a greater degree of neurologic dysfunction. Clinical features include HYDROCEPHALUS; MICROCEPHALY; deafness; cerebral calcifications; SEIZURES; and psychomotor retardation. Signs of a systemic infection may also be present at birth, including fever, rash, and hepatosplenomegaly. (From Adams et al., Principles of Neurology, 6th ed, p735)
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Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.
Nearby Words
- congenital syphilis
- congenital toxoplasma gondii infection
- congenital toxoplasma infection
- congenital toxoplasma infections
- congenital toxoplasmoses
- Congenital Toxoplasmosis
- congenital vascular malformations, central nevous system
- congenital, hereditary, and neonatal diseases and abnormalities
- congenitally
- congenite
- conger