CONGENITAL TOXOPLASMOSES
\kənd͡ʒˈɛnɪtə͡l tˈɒksəplˌazmə͡ʊzɪz], \kəndʒˈɛnɪtəl tˈɒksəplˌazməʊzɪz], \k_ə_n_dʒ_ˈɛ_n_ɪ_t_əl t_ˈɒ_k_s_ə_p_l_ˌa_z_m_əʊ_z_ɪ_z]\
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Prenatal protozoal infection with TOXOPLASMA gondii which is associated with injury to the developing fetal nervous system. The severity of this condition is related to the stage of pregnancy during which the infection occurs; first trimester infections are associated with a greater degree of neurologic dysfunction. Clinical features include HYDROCEPHALUS; MICROCEPHALY; deafness; cerebral calcifications; SEIZURES; and psychomotor retardation. Signs of a systemic infection may also be present at birth, including fever, rash, and hepatosplenomegaly. (From Adams et al., Principles of Neurology, 6th ed, p735)
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.
Nearby Words
- congenital structural myopathy
- congenital syphilis
- congenital toxoplasma gondii infection
- congenital toxoplasma infection
- congenital toxoplasma infections
- Congenital Toxoplasmoses
- congenital toxoplasmosis
- congenital vascular malformations, central nevous system
- congenital, hereditary, and neonatal diseases and abnormalities
- congenitally
- congenite