COMBINED ANTIBIOTICS
\kəmbˈa͡ɪnd ˌantɪba͡ɪˈɒtɪks], \kəmbˈaɪnd ˌantɪbaɪˈɒtɪks], \k_ə_m_b_ˈaɪ_n_d ˌa_n_t_ɪ_b_aɪ_ˈɒ_t_ɪ_k_s]\
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Combinations of antibiotics used against difficult-to-treat infections. Antibiotic combinations have been used mainly to broaden the antibacterial spectrum and prevent development of resistance. In some instances these combinations have shown lower toxicity, but drug antagonism may be one of the problems encountered by their use. They may be given simultaneously or sequentially. The drugs need not be in the same dosage form.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.