COLOCYNTH
\kˈə͡ʊləsˌɪnθ], \kˈəʊləsˌɪnθ], \k_ˈəʊ_l_ə_s_ˌɪ_n_θ]\
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By William R. Warner
By Daniel Lyons
By Willam Alexander Newman Dorland
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The fruit of Citrullus colocynthis, an annual plant of Turkey, but growing in various parts of Asia and Africa. The pulp alone is employed medicinally. Its bitter principle is colocynthin, of which it contains 14 per cent., besides extractives. Colocynth is a powerful drastic purgative and hydragogue. It enters largely into the composition of various pills and extracts, and, when modified by other ingredients, forms a very efficient and mild purgative. Colocynth is used in the form of the extract, or compound extract, usually in combination with other cathartics.
By Smith Ely Jelliffe
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.