COLISTICIN
\kˈɒlɪstˌɪsɪn], \kˈɒlɪstˌɪsɪn], \k_ˈɒ_l_ɪ_s_t_ˌɪ_s_ɪ_n]\
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Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.
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Quinones
- Hydrocarbon rings which contain two moieties position. They can be substituted in any position except at the ketone groups.