CJDS (CREUTZFELDT JAKOB DISEASE)
\sˌiːd͡ʒˌe͡ɪdˈiː krjˈuːtsfɛlt d͡ʒˈakɒb dɪzˈiːz], \sˌiːdʒˌeɪdˈiː krjˈuːtsfɛlt dʒˈakɒb dɪzˈiːz], \s_ˌiː_dʒ_ˌeɪ_d_ˈiː__ k_r_j_ˈuː_t_s_f_ɛ_l_t dʒ_ˈa_k_ɒ_b d_ɪ_z_ˈiː_z]\
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A rare transmissible encephalopathy most prevalent between the ages of 50 and 70 years. Affected individuals may present with sleep disturbances, personality changes, ATAXIA; APHASIA, visual loss, weakness, muscle atrophy, MYOCLONUS, progressive dementia, and death within one year of disease onset. A familial form exhibiting autosomal dominant inheritance and a new variant CJD (potentially associated with ENCEPHALOPATHY, BOVINE SPONGIFORM) have been described. Pathological features include prominent cerebellar and cerebral cortical spongiform degeneration and the presence of PRIONS. (From N Engl J Med, 1998 Dec 31;339 (27))
By DataStellar Co., Ltd
Nearby Words
- cize
- cjd
- cjd (creutzfeldt jakob disease)
- cjd variant (v cjd)
- cjd variants (v cjd)
- CJDs (Creutzfeldt Jakob Disease)
- cjk
- cjkv
- ck
- ckk 4
- ckr5 receptors