\sˈɜːkəmskɹˌa͡ɪbd sklˈɛɹə͡ʊdəmə], \sˈɜːkəmskɹˌaɪbd sklˈɛɹəʊdəmə], \s_ˈɜː_k_ə_m_s_k_ɹ_ˌaɪ_b_d s_k_l_ˈɛ_ɹ_əʊ_d_ə_m_ə]\
Definitions of CIRCUMSCRIBED SCLERODERMA
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A chronic, localized hardening and thickening of the skin. Lesions may be categorized as morphea (guttate, profunda, pansclerotic) or linear (with or without melorheostosis or hemiatrophy). It is twice as common in women as in men. The condition is characterized by skin ischemia, lymphocytic infiltrates, swollen collagen bundles, and thickening of the dermis with reduction of subcutaneous fat.
By DataStellar Co., Ltd
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