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a drug (trade name Tagamet) used to treat peptic ulcers by decreasing the secretion of stomach acid

a drug (trade name Tagamet) used to treat peptic ulcers by decreasing the secretion of stomach acid

A histamine congener, it competitively inhibits histamine binding to H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrin output. It also blocks the activity of cytochrome P-450.