CI898
\sˈa͡ɪ ˈe͡ɪthˈʌndɹədən nˈa͡ɪntiˈe͡ɪt], \sˈaɪ ˈeɪthˈʌndɹədən nˈaɪntiˈeɪt], \s_ˈaɪ ˈeɪ_t_h_ˈʌ_n_d_ɹ_ə_d_ə_n n_ˈaɪ_n_t_i__ˈeɪ_t]\
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A nonclassical folic acid inhibitor through its inhibition of the enzyme dihydrofolate reductase. It is being tested for efficacy as an antineoplastic agent and as an antiparasitic agent against Pneumocystis carinii pneumonia in AIDS patients. Myelosuppression is its dose-limiting toxic effect.
By DataStellar Co., Ltd
Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.