CHOLERAGENOID
\kˈə͡ʊlɹe͡ɪd͡ʒnˌɔ͡ɪd], \kˈəʊlɹeɪdʒnˌɔɪd], \k_ˈəʊ_l_ɹ_eɪ_dʒ_n_ˌɔɪ_d]\
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The enterotoxin from Vibrio cholerae. It is a protein that consists of two major components, the heavy (H) or A peptide and the light (L) or B peptide or choleragenoid. The B peptide anchors the protein to intestinal epithelial cells, while the A peptide, enters the cytoplasm, and activates adenylate cyclase, and production of cAMP. Increased levels of cAMP are thought to modulate release of fluid and electrolytes from intestinal crypt cells.
By DataStellar Co., Ltd
Word of the day
hydromorphic
- [Greek] Structurally adapted to an aquatic environment, as organs of water plants.