C1 INACTIVATORS
\sˈiː wˈɒn ɪnˈaktɪvˌe͡ɪtəz], \sˈiː wˈɒn ɪnˈaktɪvˌeɪtəz], \s_ˈiː w_ˈɒ_n ɪ_n_ˈa_k_t_ɪ_v_ˌeɪ_t_ə_z]\
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Compounds which inhibit, antagonize, or inactivate complement 1. A well-known inhibitor is a serum glycoprotein believed to be alpha-2-neuroaminoglycoprotein. It inhibits the activated (esterase) form of complement 1 as well as kinin-forming, coagulation, and fibrinolytic systems. Deficiency of this inactivator has been found in patients with hereditary angioneurotic edema. These compounds are members of the serpin superfamily.
By DataStellar Co., Ltd
