BUTHIONINE SULFOXIMINE
\bˈʌθɪˌɒna͡ɪn sʌlfˈɒksɪmˌiːn], \bˈʌθɪˌɒnaɪn sʌlfˈɒksɪmˌiːn], \b_ˈʌ_θ_ɪ__ˌɒ_n_aɪ_n s_ʌ_l_f_ˈɒ_k_s_ɪ_m_ˌiː_n]\
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A synthetic amino acid that depletes glutathione by irreversibly inhibiting gamma-glutamylcysteine synthetase. Inhibition of this enzyme is a critical step in glutathione biosynthesis. It has been shown to inhibit the proliferative response in human T-lymphocytes and inhibit macrophage activation. (J Biol Chem 1995;270 (33):1945-7)
By DataStellar Co., Ltd
Word of the day
savings and loan
- thrift institution that is required by law to make a certain percentage of its loans as home mortgages
Nearby Words
- buteo jamaicensis
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- buthalmia
- Buthionine Sulfoximine
- butirosin
- butirosin a
- butirosin b
- butirosin sulfate
- butirosin sulphate