\bˈʌpɹɪnˌɔːfiːn hˈa͡ɪdɹəklˌɔːɹa͡ɪd], \bˈʌpɹɪnˌɔːfiːn hˈaɪdɹəklˌɔːɹaɪd], \b_ˈʌ_p_ɹ_ɪ_n_ˌɔː_f_iː_n h_ˈaɪ_d_ɹ_ə_k_l_ˌɔː_ɹ_aɪ_d]\
Definitions of BUPRENORPHINE HYDROCHLORIDE
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A derivative of the opioid alkaloid THEBAINE that is a more potent and longer lasting analgesic than MORPHINE. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use.
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