BULBAR PARALYSIS
\bˈʌlbɑː pəɹˈaləsˌɪs], \bˈʌlbɑː pəɹˈaləsˌɪs], \b_ˈʌ_l_b_ɑː p_ə_ɹ_ˈa_l_ə_s_ˌɪ_s]\
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A motor neuron disease marked by progressive weakness of the muscles innervated by cranial nerves of the lower brain stem. Clinical manifestations include dysarthria, dysphagia, facial weakness, tongue weakness, and fasciculations of the tongue and facial muscles. The adult form of the disease is marked intially by bulbar weakness which progresses to involve motor neurons throughout the neuroaxis. Eventually this condition may become indistinguishable from AMYOTROPHIC LATERAL SCLEROSIS. Fazio-Londe syndrome is an inherited form of this illness which occurs in children and young adults. (Adams et al., Principles of Neurology, 6th ed, p1091; Brain 1992 Dec;115 (Pt 6):1889-1900)
By DataStellar Co., Ltd
By William R. Warner
By Willam Alexander Newman Dorland
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