BRAIN ANOXIA ISCHEMIA
\bɹˈe͡ɪn anˈɒksi͡əɹ ɪskˈiːmi͡ə], \bɹˈeɪn anˈɒksiəɹ ɪskˈiːmiə], \b_ɹ_ˈeɪ_n a_n_ˈɒ_k_s_iə_ɹ ɪ_s_k_ˈiː_m_iə]\
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A disorder characterized by a reduction in oxygen supply (HYPOXIA) combined with reduced blood flow (ISCHEMIA) to the brain. This condition may result from a localized obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ISCHEMIC ATTACK, TRANSIENT; BRAIN INFARCTION; BRAIN EDEMA; COMA; and other conditions.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.