BONE 4 CARBOXYGLUTAMIC PROTEIN
\bˈə͡ʊn fˈɔː kˌɑːbəksˌɪɡluːtˈamɪk pɹˈə͡ʊtiːn], \bˈəʊn fˈɔː kˌɑːbəksˌɪɡluːtˈamɪk pɹˈəʊtiːn], \b_ˈəʊ_n f_ˈɔː k_ˌɑː_b_ə_k_s_ˌɪ_ɡ_l_uː_t_ˈa_m_ɪ_k p_ɹ_ˈəʊ_t_iː_n]\
Definitions of BONE 4 CARBOXYGLUTAMIC PROTEIN
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Vitamin K-dependent calcium-binding protein synthesized by osteoblasts and found primarily in bone. Serum osteocalcin measurements provide a noninvasive specific marker of bone metabolism. The protein contains three residues of the amino acid gamma-carboxyglutamic acid (Gla), which, in the presence of calcium, promotes binding to hydroxyapatite and subsequent accumulation in bone matrix.
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