BIOMET400
\bˈa͡ɪɒmɪt fˈɔːhˈʌndɹəd], \bˈaɪɒmɪt fˈɔːhˈʌndɹəd], \b_ˈaɪ_ɒ_m_ɪ_t f_ˈɔː_h_ˈʌ_n_d_ɹ_ə_d]\
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A histamine congener, it competitively inhibits histamine binding to H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrin output. It also blocks the activity of cytochrome P-450.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.