BENZODIAZEPINE RECEPTORS
\bɛnzˈə͡ʊdɪˌe͡ɪzpa͡ɪn ɹɪsˈɛptəz], \bɛnzˈəʊdɪˌeɪzpaɪn ɹɪsˈɛptəz], \b_ɛ_n_z_ˈəʊ_d_ɪ__ˌeɪ_z_p_aɪ_n ɹ_ɪ_s_ˈɛ_p_t_ə_z]\
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Cell surface proteins which bind GAMMA-AMINOBUTYRIC ACID and control an integral membrane chloride channel. GABA-A receptors are the most prevalent inhibitory neurotransmitter receptors in the brain. Several isoforms have been cloned, and they belong to a superfamily which includes nicotinic receptors, glycine receptors, and 5HT-3 receptors. Most GABA-A receptors have separate modulatory sites sensitive to benzodiazepines and to barbiturates.
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