BENIGN EPILEPSY, CHILDHOOD, CENTROTEMPORAL SPIKES
\bɪnˈa͡ɪn ˈɛpɪlˌɛpsi], \bɪnˈaɪn ˈɛpɪlˌɛpsi], \b_ɪ_n_ˈaɪ_n ˈɛ_p_ɪ_l_ˌɛ_p_s_i]\
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An autosomal dominant inherited partial epilepsy syndrome with onset between age 3 and 13 years. Seizures are characterized by PARESTHESIA and tonic or clonic activity of the lower face associated with drooling and dysarthria. The episodes tend to occur at night and may become secondarily generalized. In most cases, affected children are neurologically and developmentally normal. The electroencephalogram shows characteristic high-voltage sharp waves over the central temporal regions, which are more prominent during drowsiness and sleep. In general, seizures do not continue beyond mid-adolescence. (From Epilepsia 1998 39;Suppl 4:S32-S41)
By DataStellar Co., Ltd
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